2-Carboxyimidazo[1,2-a]pyrimidine

2-Carboxyimidazo[1,2-a]pyrimidine - Names and Identifiers

Name	imidazo[1,2-a]pyrimidine-2-carboxylic acid
Synonyms	NSC296231 CHEMBRDG-BB 4014386 TIMTEC-BB SBB010439 2-Carboxyimidazo[1,2-a]pyrimidine imidazo[1,2-a]pyrimidine-2-carboxylic acid IMIDAZO[1,2-A]PYRIMIDINE-2-CARBOXYLIC ACID
CAS	64951-10-6
InChI	InChI=1/C7H5N3O2/c11-6(12)5-4-10-3-1-2-8-7(10)9-5/h1-4H,(H,11,12)

2-Carboxyimidazo[1,2-a]pyrimidine - Physico-chemical Properties

Molecular Formula	C7H5N3O2
Molar Mass	163.13
Density	1.58±0.1 g/cm3(Predicted)
pKa	-2.70±0.41(Predicted)
Storage Condition	2-8°C
Refractive Index	1.738

2-Carboxyimidazo[1,2-a]pyrimidine - Risk and Safety

Risk Codes	22 - Harmful if swallowed
WGK Germany	3
Hazard Class	IRRITANT

2-Carboxyimidazo[1,2-a]pyrimidine - Introduction

imidazo[1,2-a]pyrimidine-2-carboxylic acid is an organic compound with the chemical formula C7H5N3O2. It is a solid substance that can exist in a crystalline or powdered form. imidazo[1,2-a]pyrimidine-2-carboxylic acid is hardly soluble in water but soluble in organic solvents such as ethanol and dimethylformamide.

imidazo[1,2-a]pyrimidine-2-carboxylic acid has some important applications. First of all, it is an important intermediate compound, which is widely used in the pharmaceutical industry to synthesize anti-cancer drugs and antiviral drugs. Secondly, imidazo[1,2-a]pyrimidine-2-carboxylic acid is also applied to the preparation of organic paramagnetic materials, and can be used as a precursor for organic optical materials.

The preparation of imidazo[1,2-a]pyrimidine-2-carboxylic acid is usually achieved by chemical synthesis. A common method is by reacting 2-chloroimidazo [1,2-a]pyrimidine with sodium cyanide to give 2-cyanoacetic acid imidazo[1,2-a]pyrimidine, which is then subjected to a hydrolysis reaction to give the imidazo[1,2-a]pyrimidine-2-carboxylic acid.

Regarding the safety information of imidazo[1,2-a]pyrimidine-2-carboxylic acid, it is a chemical and needs to pay attention to normal laboratory operation methods and personal protective measures. Direct contact with skin and eyes may cause irritation, so it is necessary to wear appropriate personal protective equipment, such as laboratory gloves and goggles, when handling. In addition, imidazo[1,2-a]pyrimidine-2-carboxylic acid should be stored in a dry, dark and well-ventilated place, away from flammable substances and oxidizing agents. When using and handling this compound, relevant regulations and safe working procedures must be followed.

Last Update：2024-04-09 20:52:54